To listen to Pharmakon is to stare the beast straight in the mouth. Margaret Chardiet’s latest album starts with heavy breathing, panting and a buzzing synth that sounds more like an electroshock therapy machine. “Intent or Instinct” builds deliberately with an atonal loop gathering strength until she unleashes a nasty banshee wail. Free of too much digitized effect, it sounds truly bloodcurdling. It’s also immensely cathartic. And “Body Betrays Itself” feels like it takes over your very being, her most powerful musical statement to date. Not everything in such harsh surroundings works—“Primitive Struggle” is about as inviting as it sounds, full of coughing, spitting and heaving along to a digital heartbeat. But Chardiet can really surprise you, too. “Autoimmune” actually nudges closer to something resembling pop, like the dirtiest Trent Reznor would ever let himself get. And in the incantation of the title track, Chardiet’s actual, human voice can be heard, albeit echoed out into infinity, and the result is quite affecting, given how she shreds her voice across the rest of the record. So Bestial Burden isn’t for the faint of heart. Dismiss it and you might even get a laugh out of its relentless brutality. But give it your full attention, and it just might change you. So don’t be afraid. Dive in and let Bestial Burden swallow you whole.